Transcriptional Intermediary Factor 1γ–Induced Irisin in Skeletal Muscle Attenuates Renal Fibrosis in Diabetic Nephropathy

Transcriptional Intermediary Factor 1γ–Induced Irisin in Skeletal Muscle Attenuates Renal Fibrosis in Diabetic Nephropathy

ABSTRACT Background Transcriptional intermediary factor 1γ (TIF1γ) is a negative regulator of TGF‐β1 signalling and has been associated with patient survival in renal cell carcinoma. However, its role in diabetes mellitus (DM), particularly in diabetic nephropathy (DN), remains unclear. DN is the le...

Full description

Saved in:

Bibliographic Details
Main Authors:	Jin Hyun Kim, Seunghye Lee, Hani Jang, Sehyun Jung, Myeong Hee Jung, Jeong Won Yun, Haejin Jeon, Hyun‐Jung Kim, Se‐Ho Chang, Eun Ju Lee, Hyo‐Soo Kim
Format:	Article
Language:	English
Published:	Wiley 2025-04-01
Series:	Journal of Cachexia, Sarcopenia and Muscle
Subjects:	chronic kidney disease diabetic nephropathy fibrosis irisin muscle‐kidney crosstalk transcriptional intermediary factor 1γ
Online Access:	https://doi.org/10.1002/jcsm.13810
Tags:	Add Tag No Tags, Be the first to tag this record!

Similar Items

The cultural intermediaries reader /
Published: (2014)

Treadmill training protects valproic acid-induced autistic features via cerebellar AMPK/PPAR-γ dependent pathway and improves mitochondrial activity in mice
by: Anwaar M. Shaban, et al.
Published: (2025-07-01)

Classifications of financial intermediaries and their role in financial markets
by: N.I. Dzhuruk
Published: (2020-06-01)

Combination Effect of Caffeine Intake and Thermotherapy on the Blood Levels of Human Irisin and Fibroblast Growth Factor 21 in Healthy Males
by: Hye-Jin Lee, et al.
Published: (2025-07-01)

EUROPEAN VECTOR OF DEVELOPMENT OF NON-INSURANCE INTERMEDIARIES IN UKRAINE
by: A. Sholoiko
Published: (2017-09-01)

Irisin and neuroinflammation: Challenges and opportunities
by: Erika Yolanda Hernández Sandoval, et al.
Published: (2024-12-01)

Watt’s fair in Mumbai: intermediaries’ impact on energy justice in informal settlements
by: Ananya Peddibhotla, et al.
Published: (2024-01-01)

Irisin Attenuates Neuroinflammation Targeting the NLRP3 Inflammasome
by: Francesca Martina Filannino, et al.
Published: (2024-11-01)

Bone formation by Irisin-Poly vinyl alchol modified bioglass ceramic beads in the rabbit model
by: Seong-Su Park, et al.
Published: (2024-03-01)

Grants Supporting Innovation Intermediary Organizations
by: Éva Gajzágó, et al.
Published: (2016-08-01)

Effects of Aerobic Exercise on Irisin and Skeletal Muscle Autophagy in <i>ApoE<sup>−/−</sup></i> Mice
by: Wenxin Wang, et al.
Published: (2025-05-01)

Correlation of irisin with lipid profile in type 2 diabetes mellitus
by: Wahengbam Diana Devi, et al.
Published: (2025-02-01)

Potential effect of Irisin on sarcopenia: a systematic review
by: Yixiao Chen, et al.
Published: (2025-05-01)

Small Extracellular Vesicles Derived From Damaged Muscle Aggravate Kidney Injury Progression
by: Songling Jiang, et al.
Published: (2025-06-01)

Unveiling Hidden Aspects of Intermediary Organizations in Innovation: A Systematic Review through the Lens of Industry Taxonomy
by: Mostafa Mohseni kiasari, et al.
Published: (2024-04-01)

Sabah ve Gece Yapılan Aerobik Egzersizin Antrenmanlı Deneklerde Serum İrisin Düzeyine Etkilerinin Belirlenmesi
by: Fatih Tan, et al.
Published: (2017-03-01)

Digital piracy debunked: a short note on digital threats and intermediary liability
by: Giancarlo F. Frosio
Published: (2016-03-01)

Data intermediary
by: Heleen Janssen, et al.
Published: (2022-03-01)

Preptin and Irisin as a Metabolic Biomarkers in Juvenile Diabetes
by: Zeina Amer Ajam, et al.
Published: (2025-04-01)

Regulatory intermediaries in content moderation
by: Beatriz Kira
Published: (2025-03-01)

Irisin‐mediated muscle‐renal crosstalk as a protective mechanism against contrast‐induced acute kidney injury via cGAS‐STING signalling inhibition
by: Long Peng, et al.
Published: (2025-03-01)

Evaluation of structural-functional changes of the left ventricular myocardium in patients with arterial hypertension and obesity by the level of irisin
by: O. V. Shaparenko, et al.
Published: (2019-02-01)

Knowledge Intermediaries and Innovation Systems: Exploring a Neglected Theoretical Potential
by: Florentino Malaver, et al.
Published: (2024-12-01)

Irisin alleviated sepsis via enhancing macrophage phagocytosis and reducing inflammation levels
by: Zeen Gong, et al.
Published: (2025-08-01)

Irisin Prevents the Effects of Simulated Microgravity on Bone and Muscle Differentiation Markers
by: Lorenzo Sanesi, et al.
Published: (2025-07-01)

IRISIN, OBESITY AND TYPE II DIABETES MELLITUS
by: Zainab Fathi, et al.
Published: (2025-03-01)

The acute response of irisin to resistance and endurance exercise at both lower and higher intensities in healthy older adults
by: James E. Newman, et al.
Published: (2025-10-01)

Understanding the Role of Irisin in Longevity and Aging: A Narrative Review
by: Ana I. Plácido, et al.
Published: (2025-01-01)

Irisin: Emerging Therapeutic Targets for Cognitive Impairment-Related Diseases
by: Mei Ma, et al.
Published: (2025-01-01)

The effect of acute exercise and gender on the levels of irisin in elite athletes
by: Ş. Arıkan
Published: (2018-12-01)

The role of Irisin in modulating hypoxia-related disorders: New insights and implications for cancer therapy
by: Ghazaleh Khalili-Tanha, et al.
Published: (2025-06-01)

Association between circulating irisin level and depression: a systematic review and meta-analysis
by: Chengyan Han, et al.
Published: (2025-12-01)

Irisin restrains neuroinflammation in mouse experimental autoimmune encephalomyelitis via regulating microglia activation
by: Qiu-Xia Zhang, et al.
Published: (2025-04-01)

Study on changes in serum irisin level in free-flap transplantation and the correlation of serum irisin level with flap blood flow
by: Xianyao Tao, et al.
Published: (2024-10-01)

Classification of the Trade Intermediaries and the Variants of their Using in Supply Chains
by: Alexey Petrovich Tyapukhin, et al.
Published: (2018-04-01)

Serum irisin is positively associated with adiposity markers in obese women after single-session exercise-induced
by: Bayu Agung Pramono Pramono, et al.
Published: (2024-09-01)

The immunohistochemical evaluation of the expression of intermediary filaments, pcna, p53 and mmp-9 in feline fibrosarcomas
by: Emin Karakurt, et al.

Serum levels of irisin and nesfatin-1 in multiple sclerosis
by: Mustafa ALTAŞ, et al.
Published: (2022-02-01)

Chronic voluntary wheel running exercise ameliorates metabolic dysfunction via PGC-1α expression independently of FNDC5/irisin pathway in high fat diet-induced obese mice
by: Chaeeun Cho, et al.
Published: (2023-04-01)

Association Between Irisin Level and Cognitive Function: A Systematic Review and Meta‐Analysis
by: Chengyan Han, et al.
Published: (2025-07-01)