E2F1-driven EXOSC10 transcription promotes hepatocellular carcinoma growth and stemness: a potential therapeutic target

E2F1-driven EXOSC10 transcription promotes hepatocellular carcinoma growth and stemness: a potential therapeutic target

Abstract Background E2F Transcription Factor 1 (E2F1) is a transcription factor that plays a crucial role in the growth of many cancers, including hepatocellular carcinoma (HCC). Herein, this study probed the functions and underlying mechanisms of E2F1 in HCC tumorigenesis. Methods The expression pr...

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Bibliographic Details
Main Authors: Haoyue Deng, Dingyong Wu, Yongpeng He, Xiaolei Yu, Jifei Liu, Yanrui Zhang, Bing Leng, Xiaofeng Yuan, Liguo Xiao
Format: Article
Language:English
Published: BMC 2025-04-01
Series:Hereditas
Subjects:
E2F1
EXOSC10
HCC
Stemness
Angiogenesis
Proliferation
Online Access:https://doi.org/10.1186/s41065-025-00430-7
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https://doi.org/10.1186/s41065-025-00430-7

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