From trial data to personalized medicine: a validated framework with an application to Crohn’s disease

Abstract Clinical practice is currently guided by studies that average over patient outcomes. This may not be the best approach, as different patients may have different treatment responses. Here we extend a method for simulating clinical trials to identify optimal treatments for each patient, and w...

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Bibliographic Details
Main Authors: Vivek A. Rudrapatna, Vignesh G. Ravindranath, Douglas V. Arneson, Arman Mosenia, Atul J. Butte, Shan Wang
Format: Article
Language:English
Published: Nature Portfolio 2025-05-01
Series:npj Digital Medicine
Online Access:https://doi.org/10.1038/s41746-025-01627-w
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