One-hour extraction-free loop-mediated isothermal amplification HPV DNA assay for point-of-care testing in Maputo, Mozambique

Abstract Human papillomavirus (HPV) is responsible for nearly all cases of cervical cancer. Affordable point-of-care DNA testing is needed for cervical cancer screening in low- and middle-income countries, where most cervical cancer cases occur. HPV DNA testing typically requires complex lab infrast...

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Main Authors: Maria J. Barra, Alexis F. Wilkinson, Ariel E. Ma, Karthik Goli, Hira Atif, Nafissa M.R.B. Osman, Cesaltina Lorenzoni, Guilhermina Tivir, Eva H. Lathrop, Philip E. Castle, Ming Guo, Jane R. Montealegre, Ellen S. Baker, Mila P. Salcedo, Kathleen M. Schmeler, Rebecca R. Richards-Kortum
Format: Article
Language:English
Published: Nature Portfolio 2025-08-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-025-62454-x
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