Protective Effects of Liposomal N-Acetylcysteine against Paraquat-Induced Cytotoxicity and Gene Expression

Paraquat (PQ) is a herbicide that preferentially accumulates in the lung and exerts its cytotoxicity via the generation of reactive oxygen species (ROS). There is no specific treatment for paraquat poisoning. Attempts have been made to increase the antioxidant status in the lung using antioxidants (...

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Bibliographic Details
Main Authors: Panagiotis Mitsopoulos, Zacharias E. Suntres
Format: Article
Language:English
Published: Wiley 2011-01-01
Series:Journal of Toxicology
Online Access:http://dx.doi.org/10.1155/2011/808967
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