Autophagosome Proteins LC3A, LC3B and LC3C Have Distinct Subcellular Distribution Kinetics and Expression in Cancer Cell Lines.

LC3s (MAP1-LC3A, B and C) are structural proteins of autophagosomal membranes, widely used as biomarkers of autophagy. Whether these three LC3 proteins have a similar biological role in autophagy remains obscure. We examine in parallel the subcellular expression patterns of the three LC3 proteins in...

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Bibliographic Details
Main Authors: Michael I Koukourakis, Dimitra Kalamida, Alexandra Giatromanolaki, Christos E Zois, Efthimios Sivridis, Stamatia Pouliliou, Achilleas Mitrakas, Kevin C Gatter, Adrian L Harris
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0137675&type=printable
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