A whole blood-based functional assay to characterize immunoglobulin A effector functions

A whole blood-based functional assay to characterize immunoglobulin A effector functions

Most investigations on the immune cell-activating potency of IgA used purified total IgA and/or specific isolated cell populations. As IgA2 has been reported to be more pro-inflammatory than IgA1, we aimed to employ a fast and convenient whole blood-based assay to individually probe the capacity of...

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Bibliographic Details
Main Authors: Alice Bacon, Celia Cartagena García, Karin A. van Schie, René E. M. Toes, Jean-Marc Busnel
Format: Article
Language:English
Published: Taylor & Francis Group 2024-12-01
Series:Autoimmunity
Subjects:
Whole blood
IgA subclasses
IgA effector functions
functional assay
pre-clinical research
flow cytometry
Online Access:https://www.tandfonline.com/doi/10.1080/08916934.2024.2341629
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https://www.tandfonline.com/doi/10.1080/08916934.2024.2341629

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