Integrative functional genomics of hepatitis C virus infection identifies host dependencies in complete viral replication cycle.

Recent functional genomics studies including genome-wide small interfering RNA (siRNA) screens demonstrated that hepatitis C virus (HCV) exploits an extensive network of host factors for productive infection and propagation. How these co-opted host functions interact with various steps of HCV replic...

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Bibliographic Details
Main Authors: Qisheng Li, Yong-Yuan Zhang, Stephan Chiu, Zongyi Hu, Keng-Hsin Lan, Helen Cha, Catherine Sodroski, Fang Zhang, Ching-Sheng Hsu, Emmanuel Thomas, T Jake Liang
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-05-01
Series:PLoS Pathogens
Online Access:https://journals.plos.org/plospathogens/article/file?id=10.1371/journal.ppat.1004163&type=printable
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