Bacteriophage and Phage-Encoded Depolymerase Exhibit Antibacterial Activity Against K9-Type <i>Acinetobacter baumannii</i> in Mouse Sepsis and Burn Skin Infection Models

Bacteriophage and Phage-Encoded Depolymerase Exhibit Antibacterial Activity Against K9-Type <i>Acinetobacter baumannii</i> in Mouse Sepsis and Burn Skin Infection Models

<i>Acinetobacter baumannii</i> is a widely distributed nosocomial pathogen that causes various acute and chronic infections, particularly in immunocompromised patients. In this study, the activities of the K9-specific virulent phage AM24 and phage-encoded depolymerase DepAPK09 were asses...

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Main Authors: Alexander I. Borzilov, Nikolay V. Volozhantsev, Olga V. Korobova, Lyubov V. Kolupaeva, Evgenia S. Pereskokova, Tatiana I. Kombarova, Mikhail M. Shneider, Konstantin A. Miroshnikov, Ivan A. Dyatlov, Anastasia V. Popova
Format: Article
Language:English
Published: MDPI AG 2025-01-01
Series:Viruses
Subjects:
<i>Acinetobacter baumannii</i>
bacteriophage
depolymerase
mouse sepsis model
mouse burn skin infection model
Online Access:https://www.mdpi.com/1999-4915/17/1/70
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https://www.mdpi.com/1999-4915/17/1/70

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