Lithocholic acid controls adaptive immune responses by inhibition of Th1 activation through the Vitamin D receptor.

Bile acids are established signaling molecules next to their role in the intestinal emulsification and uptake of lipids. We here aimed to identify a potential interaction between bile acids and CD4+ Th cells, which are central in adaptive immune responses. We screened distinct bile acid species for...

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Bibliographic Details
Main Authors: Thijs W H Pols, Teresa Puchner, H Inci Korkmaz, Mariska Vos, Maarten R Soeters, Carlie J M de Vries
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2017-01-01
Series:PLoS ONE
Online Access:https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0176715&type=printable
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