Progress on the Prevention of Esophageal Stricture after Endoscopic Submucosal Dissection

Endoscopic submucosal dissection (ESD) has been widely accepted as an effective, minimally invasive treatment for superficial esophageal cancers. However, esophageal stricture often occurs in patients with large mucosal defects after ESD. In this review, we discuss various approaches recently resear...

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Main Authors: Peina Shi, Xiaoyun Ding
Format: Article
Language:English
Published: Wiley 2018-01-01
Series:Gastroenterology Research and Practice
Online Access:http://dx.doi.org/10.1155/2018/1696849
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author Peina Shi
Xiaoyun Ding
author_facet Peina Shi
Xiaoyun Ding
author_sort Peina Shi
collection DOAJ
description Endoscopic submucosal dissection (ESD) has been widely accepted as an effective, minimally invasive treatment for superficial esophageal cancers. However, esophageal stricture often occurs in patients with large mucosal defects after ESD. In this review, we discuss various approaches recently researched to prevent esophageal strictures after ESD. These approaches can be classified as pharmacological treatments, esophageal stent treatments, and tissue engineering approaches. Most of the preventive approaches still have their limitations and require further research. With the improvement of current therapies, ESD can be more widely utilized as a minimally invasive treatment with minimal complications.
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institution Kabale University
issn 1687-6121
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publishDate 2018-01-01
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series Gastroenterology Research and Practice
spelling doaj-art-ea326c89a9d54ccb94271f2b59b236c82025-02-03T05:44:56ZengWileyGastroenterology Research and Practice1687-61211687-630X2018-01-01201810.1155/2018/16968491696849Progress on the Prevention of Esophageal Stricture after Endoscopic Submucosal DissectionPeina Shi0Xiaoyun Ding1Medical School, Ningbo University, Ningbo, Zhejiang, ChinaGastroenterology Department, Ningbo First Hospital, Ningbo, Zhejiang, ChinaEndoscopic submucosal dissection (ESD) has been widely accepted as an effective, minimally invasive treatment for superficial esophageal cancers. However, esophageal stricture often occurs in patients with large mucosal defects after ESD. In this review, we discuss various approaches recently researched to prevent esophageal strictures after ESD. These approaches can be classified as pharmacological treatments, esophageal stent treatments, and tissue engineering approaches. Most of the preventive approaches still have their limitations and require further research. With the improvement of current therapies, ESD can be more widely utilized as a minimally invasive treatment with minimal complications.http://dx.doi.org/10.1155/2018/1696849
spellingShingle Peina Shi
Xiaoyun Ding
Progress on the Prevention of Esophageal Stricture after Endoscopic Submucosal Dissection
Gastroenterology Research and Practice
title Progress on the Prevention of Esophageal Stricture after Endoscopic Submucosal Dissection
title_full Progress on the Prevention of Esophageal Stricture after Endoscopic Submucosal Dissection
title_fullStr Progress on the Prevention of Esophageal Stricture after Endoscopic Submucosal Dissection
title_full_unstemmed Progress on the Prevention of Esophageal Stricture after Endoscopic Submucosal Dissection
title_short Progress on the Prevention of Esophageal Stricture after Endoscopic Submucosal Dissection
title_sort progress on the prevention of esophageal stricture after endoscopic submucosal dissection
url http://dx.doi.org/10.1155/2018/1696849
work_keys_str_mv AT peinashi progressonthepreventionofesophagealstrictureafterendoscopicsubmucosaldissection
AT xiaoyunding progressonthepreventionofesophagealstrictureafterendoscopicsubmucosaldissection