Limiting the development of anti-cancer drug resistance in a spatial model of micrometastases
While chemoresistance in primary tumors is well-studied, much less is known about the influence of systemic chemotherapy on the development of drug resistance at metastatic sites. In this work, we use a hybrid spatial model of tumor response to a DNA damaging drug to study how the development of che...
Saved in:
Main Authors: | Ami B. Shah, Katarzyna A. Rejniak, Jana L. Gevertz |
---|---|
Format: | Article |
Language: | English |
Published: |
AIMS Press
2016-07-01
|
Series: | Mathematical Biosciences and Engineering |
Subjects: | |
Online Access: | https://www.aimspress.com/article/doi/10.3934/mbe.2016038 |
Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
Similar Items
-
On drug resistance and metronomic chemotherapy: A mathematical modeling and optimal control approach
by: Urszula Ledzewicz, et al.
Published: (2017-01-01) -
Dynamics and control of a mathematical model for metronomic chemotherapy
by: Urszula Ledzewicz, et al.
Published: (2015-07-01) -
Sulforaphane in alternative cancer chemotherapy: From carcinogenesis suppression to drug resistance reversal
by: Seyed Mohammad Doodmani, et al.
Published: (2025-01-01) -
Calibration of ionization chamber in megavoltage x-ray field of medical linear accelerator
by: Pham Hong-Lam, et al.
Published: (2024-01-01) -
Omega-3 fatty acids: molecular weapons against chemoresistance in breast cancer
by: Vittoria Marchio, et al.
Published: (2025-01-01)