Limiting the development of anti-cancer drug resistance in a spatial model of micrometastases

While chemoresistance in primary tumors is well-studied, much less is known about the influence of systemic chemotherapy on the development of drug resistance at metastatic sites. In this work, we use a hybrid spatial model of tumor response to a DNA damaging drug to study how the development of che...

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Bibliographic Details
Main Authors: Ami B. Shah, Katarzyna A. Rejniak, Jana L. Gevertz
Format: Article
Language:English
Published: AIMS Press 2016-07-01
Series:Mathematical Biosciences and Engineering
Subjects:
Online Access:https://www.aimspress.com/article/doi/10.3934/mbe.2016038
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