Limiting the development of anti-cancer drug resistance in a spatial model of micrometastases
While chemoresistance in primary tumors is well-studied, much less is known about the influence of systemic chemotherapy on the development of drug resistance at metastatic sites. In this work, we use a hybrid spatial model of tumor response to a DNA damaging drug to study how the development of che...
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Main Authors: | , , |
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Format: | Article |
Language: | English |
Published: |
AIMS Press
2016-07-01
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Series: | Mathematical Biosciences and Engineering |
Subjects: | |
Online Access: | https://www.aimspress.com/article/doi/10.3934/mbe.2016038 |
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