Fabrication of Bilayer Coating of Poly(3,4-ethylenedioxythiophene)-Halloysite/Chitosan and Mg2+/Sr2+-Doped HAP on Titanium Alloy for Biomedical Implant Applications: Physicochemical and In Vitro Biological Performances Studies
The prime objective of the present work is to develop biocompatible overlayer-deposited titanium alloys to replace already available titanium alloy-based biomaterials for implantation applications. Here, we prefer to use a bilayer coating on titanium alloys instead of single coating. The adhesion an...
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| Format: | Article |
| Language: | English |
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Wiley
2018-01-01
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| Series: | Journal of Chemistry |
| Online Access: | http://dx.doi.org/10.1155/2018/9813827 |
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| author | Manickam Chozhanathmisra Dharman Govindaraj Palanisamy Karthikeyan Kannaiyan Pandian Liviu Mitu Rangappan Rajavel |
| author_facet | Manickam Chozhanathmisra Dharman Govindaraj Palanisamy Karthikeyan Kannaiyan Pandian Liviu Mitu Rangappan Rajavel |
| author_sort | Manickam Chozhanathmisra |
| collection | DOAJ |
| description | The prime objective of the present work is to develop biocompatible overlayer-deposited titanium alloys to replace already available titanium alloy-based biomaterials for implantation applications. Here, we prefer to use a bilayer coating on titanium alloys instead of single coating. The adhesion and biocompatibility of titanium alloy is improved by coating with a bilayer, for example, PEDOT-HNT/CS-MHA composite using the electrochemical deposition method. Corrosion behavior of the PEDOT-HNT/CS-MHA bilayer composite coating was investigated in the PBS medium by polarization studies. The functional groups, phase purity, surface morphology, and wettability of the PEDOT-HNT/CS-MHA were characterized by various instrumental techniques like FTIR, XRD, SEM, and contact angle techniques. From the above studies, it is proved that PEDOT-HNT/CS-MHA-coated Ti alloy showing a better biocompatibility and corrosion resistance than the PEDOT-HNT-deposited Ti alloy. In addition, the in vitro bactericidal and cell viability studies were also carried out to further confirm the biocompatibility of the protective coating. Hence, the bilayer deposition has shown excellent stability and biocompatibility and can be used for the potential biomaterials for orthopedics applications. |
| format | Article |
| id | doaj-art-ea02514d81f844efb9d6fe914dbafb6c |
| institution | Kabale University |
| issn | 2090-9063 2090-9071 |
| language | English |
| publishDate | 2018-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Journal of Chemistry |
| spelling | doaj-art-ea02514d81f844efb9d6fe914dbafb6c2025-02-03T06:11:27ZengWileyJournal of Chemistry2090-90632090-90712018-01-01201810.1155/2018/98138279813827Fabrication of Bilayer Coating of Poly(3,4-ethylenedioxythiophene)-Halloysite/Chitosan and Mg2+/Sr2+-Doped HAP on Titanium Alloy for Biomedical Implant Applications: Physicochemical and In Vitro Biological Performances StudiesManickam Chozhanathmisra0Dharman Govindaraj1Palanisamy Karthikeyan2Kannaiyan Pandian3Liviu Mitu4Rangappan Rajavel5Department of Chemistry, Periyar University, Salem 636 011, Tamilnadu, IndiaBiomaterials in Medicinal Chemistry Lab, Department of Natural Products Chemistry, School of Chemistry, Madurai Kamaraj University, Madurai 625021, IndiaDepartment of Chemistry, Periyar University Constituent College of Arts and Science Idappadi, Salem 637 102, Tamilnadu, IndiaDepartment of Inorganic Chemistry, University of Madras, Guindy Campus, Chennai 600025, Tamilnadu, IndiaDepartment of Physics & Chemistry, University of Pitesti, Pitesti 110040, RomaniaDepartment of Chemistry, Periyar University, Salem 636 011, Tamilnadu, IndiaThe prime objective of the present work is to develop biocompatible overlayer-deposited titanium alloys to replace already available titanium alloy-based biomaterials for implantation applications. Here, we prefer to use a bilayer coating on titanium alloys instead of single coating. The adhesion and biocompatibility of titanium alloy is improved by coating with a bilayer, for example, PEDOT-HNT/CS-MHA composite using the electrochemical deposition method. Corrosion behavior of the PEDOT-HNT/CS-MHA bilayer composite coating was investigated in the PBS medium by polarization studies. The functional groups, phase purity, surface morphology, and wettability of the PEDOT-HNT/CS-MHA were characterized by various instrumental techniques like FTIR, XRD, SEM, and contact angle techniques. From the above studies, it is proved that PEDOT-HNT/CS-MHA-coated Ti alloy showing a better biocompatibility and corrosion resistance than the PEDOT-HNT-deposited Ti alloy. In addition, the in vitro bactericidal and cell viability studies were also carried out to further confirm the biocompatibility of the protective coating. Hence, the bilayer deposition has shown excellent stability and biocompatibility and can be used for the potential biomaterials for orthopedics applications.http://dx.doi.org/10.1155/2018/9813827 |
| spellingShingle | Manickam Chozhanathmisra Dharman Govindaraj Palanisamy Karthikeyan Kannaiyan Pandian Liviu Mitu Rangappan Rajavel Fabrication of Bilayer Coating of Poly(3,4-ethylenedioxythiophene)-Halloysite/Chitosan and Mg2+/Sr2+-Doped HAP on Titanium Alloy for Biomedical Implant Applications: Physicochemical and In Vitro Biological Performances Studies Journal of Chemistry |
| title | Fabrication of Bilayer Coating of Poly(3,4-ethylenedioxythiophene)-Halloysite/Chitosan and Mg2+/Sr2+-Doped HAP on Titanium Alloy for Biomedical Implant Applications: Physicochemical and In Vitro Biological Performances Studies |
| title_full | Fabrication of Bilayer Coating of Poly(3,4-ethylenedioxythiophene)-Halloysite/Chitosan and Mg2+/Sr2+-Doped HAP on Titanium Alloy for Biomedical Implant Applications: Physicochemical and In Vitro Biological Performances Studies |
| title_fullStr | Fabrication of Bilayer Coating of Poly(3,4-ethylenedioxythiophene)-Halloysite/Chitosan and Mg2+/Sr2+-Doped HAP on Titanium Alloy for Biomedical Implant Applications: Physicochemical and In Vitro Biological Performances Studies |
| title_full_unstemmed | Fabrication of Bilayer Coating of Poly(3,4-ethylenedioxythiophene)-Halloysite/Chitosan and Mg2+/Sr2+-Doped HAP on Titanium Alloy for Biomedical Implant Applications: Physicochemical and In Vitro Biological Performances Studies |
| title_short | Fabrication of Bilayer Coating of Poly(3,4-ethylenedioxythiophene)-Halloysite/Chitosan and Mg2+/Sr2+-Doped HAP on Titanium Alloy for Biomedical Implant Applications: Physicochemical and In Vitro Biological Performances Studies |
| title_sort | fabrication of bilayer coating of poly 3 4 ethylenedioxythiophene halloysite chitosan and mg2 sr2 doped hap on titanium alloy for biomedical implant applications physicochemical and in vitro biological performances studies |
| url | http://dx.doi.org/10.1155/2018/9813827 |
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