OXA β-lactamases from Acinetobacter spp. are membrane bound and secreted into outer membrane vesicles
ABSTRACT β-lactamases from Gram-negative bacteria are generally regarded as soluble, periplasmic enzymes. NDMs have been exceptionally characterized as lipoproteins anchored to the outer membrane. A bioinformatics study on all sequenced β-lactamases was performed that revealed a predominance of puta...
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Main Authors: | Lucia Capodimonte, Fernando Teixeira Pinto Meireles, Guillermo Bahr, Robert A. Bonomo, Matteo Dal Peraro, Carolina López, Alejandro J. Vila |
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Format: | Article |
Language: | English |
Published: |
American Society for Microbiology
2025-02-01
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Series: | mBio |
Subjects: | |
Online Access: | https://journals.asm.org/doi/10.1128/mbio.03343-24 |
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