The HOPS and vCLAMP protein Vam6 connects polyphosphate with mitochondrial function and oxidative stress resistance in Cryptococcus neoformans

The HOPS and vCLAMP protein Vam6 connects polyphosphate with mitochondrial function and oxidative stress resistance in Cryptococcus neoformans

ABSTRACT Cryptococcus neoformans is considered one of the most dangerous fungal threats to human health, and the World Health Organization recently ranked it in the critical priority group for perceived public health importance. Proliferation of C. neoformans within mammalian hosts is supported by i...

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Bibliographic Details
Main Authors: Eddy Sánchez-León, Kabir Bhalla, Guanggan Hu, Christopher W. J. Lee, Melissa Lagace, Won Hee Jung, James W. Kronstad
Format: Article
Language:English
Published: American Society for Microbiology 2025-04-01
Series:mBio
Subjects:
Vam6
Vtc2
mitochondria
vacuole
oxidative stress
polyphosphate
Online Access:https://journals.asm.org/doi/10.1128/mbio.00328-25
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https://journals.asm.org/doi/10.1128/mbio.00328-25

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