Total Psoas Area Predicts Complications following Radical Cystectomy
Purpose. To determine whether total psoas area (TPA), a simple estimate of muscle mass, is associated with complications after radical cystectomy. Materials and Methods. Patients who underwent radical cystectomy at our institution from 2011 to 2012 were retrospectively identified. Total psoas area w...
Saved in:
| Main Authors: | , , , , , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Wiley
2015-01-01
|
| Series: | Advances in Urology |
| Online Access: | http://dx.doi.org/10.1155/2015/901851 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| _version_ | 1832551770912456704 |
|---|---|
| author | Timothy D. Lyon Nicholas J. Farber Leo C. Chen Thomas W. Fuller Benjamin J. Davies Jeffrey R. Gingrich Ronald L. Hrebinko Jodi K. Maranchie Jennifer M. Taylor Tatum V. Tarin |
| author_facet | Timothy D. Lyon Nicholas J. Farber Leo C. Chen Thomas W. Fuller Benjamin J. Davies Jeffrey R. Gingrich Ronald L. Hrebinko Jodi K. Maranchie Jennifer M. Taylor Tatum V. Tarin |
| author_sort | Timothy D. Lyon |
| collection | DOAJ |
| description | Purpose. To determine whether total psoas area (TPA), a simple estimate of muscle mass, is associated with complications after radical cystectomy. Materials and Methods. Patients who underwent radical cystectomy at our institution from 2011 to 2012 were retrospectively identified. Total psoas area was measured on preoperative CT scans and normalized for patient height. Multivariable logistic regression was used to determine whether TPA was a predictor of 90-day postoperative complications. Overall survival was compared between TPA quartiles. Results. 135 patients were identified for analysis. Median follow-up was 24 months (IQR: 6–37 months). Overall 90-day complication rate was 56% (75/135). TPA was significantly lower for patients who experienced any complication (7.8 cm2/m2 versus 8.8 cm2/m2, P=0.023) and an infectious complication (7.0 cm2/m2 versus 8.7 cm2/m2, P=0.032) than those who did not. On multivariable analysis, TPA (adjusted OR 0.70 (95% CI 0.56–0.89), P=0.003) and Charlson comorbidity index (adjusted OR 1.34 (95% CI 1.01–1.79), P=0.045) were independently associated with 90-day complications. TPA was not a predictor of overall survival. Conclusions. Low TPA is associated with infectious complications and is an independent predictor of experiencing a postoperative complication following radical cystectomy. |
| format | Article |
| id | doaj-art-e9ed5abcc60d4c53a87cf5201f8a73f3 |
| institution | Kabale University |
| issn | 1687-6369 1687-6377 |
| language | English |
| publishDate | 2015-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Advances in Urology |
| spelling | doaj-art-e9ed5abcc60d4c53a87cf5201f8a73f32025-02-03T06:00:40ZengWileyAdvances in Urology1687-63691687-63772015-01-01201510.1155/2015/901851901851Total Psoas Area Predicts Complications following Radical CystectomyTimothy D. Lyon0Nicholas J. Farber1Leo C. Chen2Thomas W. Fuller3Benjamin J. Davies4Jeffrey R. Gingrich5Ronald L. Hrebinko6Jodi K. Maranchie7Jennifer M. Taylor8Tatum V. Tarin9Department of Urology, University of Pittsburgh, Pittsburgh, PA, USADivision of Urology, Rutgers Robert Wood Johnson Medical School, New Brunswick, NJ, USAUniversity of Pittsburgh School of Medicine, Pittsburgh, PA, USADepartment of Urology, University of Pittsburgh, Pittsburgh, PA, USADepartment of Urology, University of Pittsburgh, Pittsburgh, PA, USADepartment of Urology, University of Pittsburgh, Pittsburgh, PA, USADepartment of Urology, University of Pittsburgh, Pittsburgh, PA, USADepartment of Urology, University of Pittsburgh, Pittsburgh, PA, USADepartment of Urology, Baylor College of Medicine, Houston, TX, USADepartment of Urology, University of Pittsburgh, Pittsburgh, PA, USAPurpose. To determine whether total psoas area (TPA), a simple estimate of muscle mass, is associated with complications after radical cystectomy. Materials and Methods. Patients who underwent radical cystectomy at our institution from 2011 to 2012 were retrospectively identified. Total psoas area was measured on preoperative CT scans and normalized for patient height. Multivariable logistic regression was used to determine whether TPA was a predictor of 90-day postoperative complications. Overall survival was compared between TPA quartiles. Results. 135 patients were identified for analysis. Median follow-up was 24 months (IQR: 6–37 months). Overall 90-day complication rate was 56% (75/135). TPA was significantly lower for patients who experienced any complication (7.8 cm2/m2 versus 8.8 cm2/m2, P=0.023) and an infectious complication (7.0 cm2/m2 versus 8.7 cm2/m2, P=0.032) than those who did not. On multivariable analysis, TPA (adjusted OR 0.70 (95% CI 0.56–0.89), P=0.003) and Charlson comorbidity index (adjusted OR 1.34 (95% CI 1.01–1.79), P=0.045) were independently associated with 90-day complications. TPA was not a predictor of overall survival. Conclusions. Low TPA is associated with infectious complications and is an independent predictor of experiencing a postoperative complication following radical cystectomy.http://dx.doi.org/10.1155/2015/901851 |
| spellingShingle | Timothy D. Lyon Nicholas J. Farber Leo C. Chen Thomas W. Fuller Benjamin J. Davies Jeffrey R. Gingrich Ronald L. Hrebinko Jodi K. Maranchie Jennifer M. Taylor Tatum V. Tarin Total Psoas Area Predicts Complications following Radical Cystectomy Advances in Urology |
| title | Total Psoas Area Predicts Complications following Radical Cystectomy |
| title_full | Total Psoas Area Predicts Complications following Radical Cystectomy |
| title_fullStr | Total Psoas Area Predicts Complications following Radical Cystectomy |
| title_full_unstemmed | Total Psoas Area Predicts Complications following Radical Cystectomy |
| title_short | Total Psoas Area Predicts Complications following Radical Cystectomy |
| title_sort | total psoas area predicts complications following radical cystectomy |
| url | http://dx.doi.org/10.1155/2015/901851 |
| work_keys_str_mv | AT timothydlyon totalpsoasareapredictscomplicationsfollowingradicalcystectomy AT nicholasjfarber totalpsoasareapredictscomplicationsfollowingradicalcystectomy AT leocchen totalpsoasareapredictscomplicationsfollowingradicalcystectomy AT thomaswfuller totalpsoasareapredictscomplicationsfollowingradicalcystectomy AT benjaminjdavies totalpsoasareapredictscomplicationsfollowingradicalcystectomy AT jeffreyrgingrich totalpsoasareapredictscomplicationsfollowingradicalcystectomy AT ronaldlhrebinko totalpsoasareapredictscomplicationsfollowingradicalcystectomy AT jodikmaranchie totalpsoasareapredictscomplicationsfollowingradicalcystectomy AT jennifermtaylor totalpsoasareapredictscomplicationsfollowingradicalcystectomy AT tatumvtarin totalpsoasareapredictscomplicationsfollowingradicalcystectomy |