Highlights in IBD Epidemiology and Its Natural History in the Paediatric Age
Background. The number of patients of all age brackets diagnosed with Inflammatory Bowel Disease (IBD) has risen dramatically worldwide over the past 50 years. IBD’s changing epidemiology suggests that environmental factors play a major role in modifying disease expression. Aim. To review studies ca...
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| Format: | Article |
| Language: | English |
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Wiley
2013-01-01
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| Series: | Gastroenterology Research and Practice |
| Online Access: | http://dx.doi.org/10.1155/2013/829040 |
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| author | Marco Gasparetto Graziella Guariso |
| author_facet | Marco Gasparetto Graziella Guariso |
| author_sort | Marco Gasparetto |
| collection | DOAJ |
| description | Background. The number of patients of all age brackets diagnosed with Inflammatory Bowel Disease (IBD) has risen dramatically worldwide over the past 50 years. IBD’s changing epidemiology suggests that environmental factors play a major role in modifying disease expression. Aim. To review studies carried out worldwide analyzing IBD epidemiology. Methods. A Medline search indicating as keywords “Inflammatory Bowel Disease,” “epidemiology,” “natural history,” “Crohn’s Disease,” “Ulcerative Colitis,” and “IBD Unclassified” was performed. A selection of clinical cohort and systematic review studies that were carried out between 2002 and 2013 was reviewed. Studies referring to an earlier date were also considered whenever the data were relevant to our review. Results. The current mean prevalence of IBD in the total population of Western countries is estimated at 1/1,000. The highest prevalence and incidence rates of IBD worldwide are reported from Canada. Just as urbanization and socioeconomic development, the incidence of IBD is rising in China. Conclusions. Multicenter national registers and international networks can provide information on IBD epidemiology and lead to hypotheses about its causes and possible management strategies. The rising trend in the disease’s incidence in developing nations suggests that its epidemiological evolution is linked to industrialization and modern Westernized lifestyles. |
| format | Article |
| id | doaj-art-e9ec37aef2234f328050dae3a86922dd |
| institution | Kabale University |
| issn | 1687-6121 1687-630X |
| language | English |
| publishDate | 2013-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Gastroenterology Research and Practice |
| spelling | doaj-art-e9ec37aef2234f328050dae3a86922dd2025-02-03T06:05:53ZengWileyGastroenterology Research and Practice1687-61211687-630X2013-01-01201310.1155/2013/829040829040Highlights in IBD Epidemiology and Its Natural History in the Paediatric AgeMarco Gasparetto0Graziella Guariso1Unit of Paediatric Gastroenterology, Digestive Endoscopy, Hepatology, and Care of Children with Liver Transplantation, Department of Women’s and Children’s Health, University Hospital of Padova, Via Giustiniani 3, 35128 Padova, ItalyUnit of Paediatric Gastroenterology, Digestive Endoscopy, Hepatology, and Care of Children with Liver Transplantation, Department of Women’s and Children’s Health, University Hospital of Padova, Via Giustiniani 3, 35128 Padova, ItalyBackground. The number of patients of all age brackets diagnosed with Inflammatory Bowel Disease (IBD) has risen dramatically worldwide over the past 50 years. IBD’s changing epidemiology suggests that environmental factors play a major role in modifying disease expression. Aim. To review studies carried out worldwide analyzing IBD epidemiology. Methods. A Medline search indicating as keywords “Inflammatory Bowel Disease,” “epidemiology,” “natural history,” “Crohn’s Disease,” “Ulcerative Colitis,” and “IBD Unclassified” was performed. A selection of clinical cohort and systematic review studies that were carried out between 2002 and 2013 was reviewed. Studies referring to an earlier date were also considered whenever the data were relevant to our review. Results. The current mean prevalence of IBD in the total population of Western countries is estimated at 1/1,000. The highest prevalence and incidence rates of IBD worldwide are reported from Canada. Just as urbanization and socioeconomic development, the incidence of IBD is rising in China. Conclusions. Multicenter national registers and international networks can provide information on IBD epidemiology and lead to hypotheses about its causes and possible management strategies. The rising trend in the disease’s incidence in developing nations suggests that its epidemiological evolution is linked to industrialization and modern Westernized lifestyles.http://dx.doi.org/10.1155/2013/829040 |
| spellingShingle | Marco Gasparetto Graziella Guariso Highlights in IBD Epidemiology and Its Natural History in the Paediatric Age Gastroenterology Research and Practice |
| title | Highlights in IBD Epidemiology and Its Natural History in the Paediatric Age |
| title_full | Highlights in IBD Epidemiology and Its Natural History in the Paediatric Age |
| title_fullStr | Highlights in IBD Epidemiology and Its Natural History in the Paediatric Age |
| title_full_unstemmed | Highlights in IBD Epidemiology and Its Natural History in the Paediatric Age |
| title_short | Highlights in IBD Epidemiology and Its Natural History in the Paediatric Age |
| title_sort | highlights in ibd epidemiology and its natural history in the paediatric age |
| url | http://dx.doi.org/10.1155/2013/829040 |
| work_keys_str_mv | AT marcogasparetto highlightsinibdepidemiologyanditsnaturalhistoryinthepaediatricage AT graziellaguariso highlightsinibdepidemiologyanditsnaturalhistoryinthepaediatricage |