Performance of Surgical Stress Index during Sevoflurane-Fentanyl and Isoflurane-Fentanyl Anesthesia

The performance of recently introduced Surgical Stress Index (SSI), based on heart rate and photoplethysmography, was estimated during sevoflurane-fentanyl and isoflurane-fentanyl anesthesia during surgical procedures. Forty ASA I–III patients were enrolled. Anesthesia was induced with fentanyl 2 μg...

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Main Authors: S. Mustola, T. Parkkari, K. Uutela, M. Huiku, M. Kymäläinen, J. Toivonen
Format: Article
Language:English
Published: Wiley 2010-01-01
Series:Anesthesiology Research and Practice
Online Access:http://dx.doi.org/10.1155/2010/810721
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author S. Mustola
T. Parkkari
K. Uutela
M. Huiku
M. Kymäläinen
J. Toivonen
author_facet S. Mustola
T. Parkkari
K. Uutela
M. Huiku
M. Kymäläinen
J. Toivonen
author_sort S. Mustola
collection DOAJ
description The performance of recently introduced Surgical Stress Index (SSI), based on heart rate and photoplethysmography, was estimated during sevoflurane-fentanyl and isoflurane-fentanyl anesthesia during surgical procedures. Forty ASA I–III patients were enrolled. Anesthesia was induced with fentanyl 2 μg kg−1 and thiopentone 3–5 mg kg−1. Tracheal intubation was performed 5 minutes after fentanyl bolus. Patients were randomly allocated to receive sevoflurane (n=20) or isoflurane (n=20) in 30% oxygen/air. State entropy was kept at 40–60, target being 50. During surgery, fentanyl boluses 1.5 μg kg−1 were given at 30–40-minute intervals. SSI increased significantly after intubation. During surgery, the decrease of SSI after fentanyl boluses was similar in sevoflurane and isoflurane groups but SSI values were higher in sevoflurane than in isoflurane group. Tracheal intubation, skin incision, and surgical stimuli increased SSI from baseline, indicating that nociceptive stimuli increase SSI. Fentanyl boluses during surgery decreased SSI, indicating that increasing analgesia decreases SSI.
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spelling doaj-art-e9b26ea7056a4ac3b55ab70ef8c81f102025-02-03T01:24:19ZengWileyAnesthesiology Research and Practice1687-69621687-69702010-01-01201010.1155/2010/810721810721Performance of Surgical Stress Index during Sevoflurane-Fentanyl and Isoflurane-Fentanyl AnesthesiaS. Mustola0T. Parkkari1K. Uutela2M. Huiku3M. Kymäläinen4J. Toivonen5Department of Anesthesia, South Carelia Central Hospital, Valtokäkelänkatu 1, 53130 Lappeenranta, FinlandClinical Research, GE Healthcare Finland Oy, P.O. Box 900, 00031 GE Helsinki, FinlandClinical Research, GE Healthcare Finland Oy, P.O. Box 900, 00031 GE Helsinki, FinlandClinical Research, GE Healthcare Finland Oy, P.O. Box 900, 00031 GE Helsinki, FinlandClinical Research, GE Healthcare Finland Oy, P.O. Box 900, 00031 GE Helsinki, FinlandDepartment of Anesthesia, South Carelia Central Hospital, Valtokäkelänkatu 1, 53130 Lappeenranta, FinlandThe performance of recently introduced Surgical Stress Index (SSI), based on heart rate and photoplethysmography, was estimated during sevoflurane-fentanyl and isoflurane-fentanyl anesthesia during surgical procedures. Forty ASA I–III patients were enrolled. Anesthesia was induced with fentanyl 2 μg kg−1 and thiopentone 3–5 mg kg−1. Tracheal intubation was performed 5 minutes after fentanyl bolus. Patients were randomly allocated to receive sevoflurane (n=20) or isoflurane (n=20) in 30% oxygen/air. State entropy was kept at 40–60, target being 50. During surgery, fentanyl boluses 1.5 μg kg−1 were given at 30–40-minute intervals. SSI increased significantly after intubation. During surgery, the decrease of SSI after fentanyl boluses was similar in sevoflurane and isoflurane groups but SSI values were higher in sevoflurane than in isoflurane group. Tracheal intubation, skin incision, and surgical stimuli increased SSI from baseline, indicating that nociceptive stimuli increase SSI. Fentanyl boluses during surgery decreased SSI, indicating that increasing analgesia decreases SSI.http://dx.doi.org/10.1155/2010/810721
spellingShingle S. Mustola
T. Parkkari
K. Uutela
M. Huiku
M. Kymäläinen
J. Toivonen
Performance of Surgical Stress Index during Sevoflurane-Fentanyl and Isoflurane-Fentanyl Anesthesia
Anesthesiology Research and Practice
title Performance of Surgical Stress Index during Sevoflurane-Fentanyl and Isoflurane-Fentanyl Anesthesia
title_full Performance of Surgical Stress Index during Sevoflurane-Fentanyl and Isoflurane-Fentanyl Anesthesia
title_fullStr Performance of Surgical Stress Index during Sevoflurane-Fentanyl and Isoflurane-Fentanyl Anesthesia
title_full_unstemmed Performance of Surgical Stress Index during Sevoflurane-Fentanyl and Isoflurane-Fentanyl Anesthesia
title_short Performance of Surgical Stress Index during Sevoflurane-Fentanyl and Isoflurane-Fentanyl Anesthesia
title_sort performance of surgical stress index during sevoflurane fentanyl and isoflurane fentanyl anesthesia
url http://dx.doi.org/10.1155/2010/810721
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