Islet delta-cell architecture is remodelled in the human pancreas during type 1 diabetes

Abstract Delta cells participate in regulating hormone secretion in adjacent alpha- and beta cells and a general assumption is that cells with a shorter distance to the secreting cell receive a higher concentration of the secretory compounds. Isolated islets obtained from donors with type 1 diabetes...

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Bibliographic Details
Main Authors: Angie Tegehall, Olle Korsgren, Sofie Ingvast, Gajana Gasparyan, Louise Granlund, Marcus Lundberg
Format: Article
Language:English
Published: Nature Portfolio 2025-06-01
Series:Scientific Reports
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Online Access:https://doi.org/10.1038/s41598-025-04471-w
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