Luteolin Pretreatment Attenuates Hepatic Ischemia-Reperfusion Injury in Mice by Inhibiting Inflammation, Autophagy, and Apoptosis via the ERK/PPARα Pathway

Luteolin Pretreatment Attenuates Hepatic Ischemia-Reperfusion Injury in Mice by Inhibiting Inflammation, Autophagy, and Apoptosis via the ERK/PPARα Pathway

Hepatic ischemia-reperfusion (IR) injury is a clinically significant process that frequently occurs in liver transplantation, partial hepatectomy, and hemorrhagic shock. The aim of this study was to explore the effectiveness of luteolin in hepatic IR injury and the underlying mechanism. BALB/c mice...

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Main Authors: Yuhui Jiang, Wenjuan Yang, Jiameng Ding, Jie Ji, Liwei Wu, Yuanyuan Zheng, Yan Li, Ziqi Cheng, Jie Zhang, Qiang Yu, Jiao Feng, Jingjing Li, Jianye Wu, Yingqun Zhou, Chuanyong Guo
Format: Article
Language:English
Published: Wiley 2022-01-01
Series:PPAR Research
Online Access:http://dx.doi.org/10.1155/2022/8161946
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http://dx.doi.org/10.1155/2022/8161946

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