Sevoflurane Preconditioning Rescues PKMζ Gene Expression from Broad Hypoxia-Induced mRNA Downregulation Correlating with Improved Neuronal Recovery

Sevoflurane Preconditioning Rescues PKMζ Gene Expression from Broad Hypoxia-Induced mRNA Downregulation Correlating with Improved Neuronal Recovery

Hypoxia due to stroke is a major cause of neuronal damage, leading to loss of cognition and other brain functions. Sevoflurane preconditioning improves recovery after hypoxia. Hypoxia interferes with protein expression at the translational level; however, its effect on mRNA levels for neuronal prote...

Full description

Saved in:
Bibliographic Details
Main Authors: Joan Y. Hou, Kim D. Allen, A. Iván Hernandez, James E. Cottrell, Ira S. Kass
Format: Article
Language:English
Published: MDPI AG 2025-01-01
Series:NeuroSci
Subjects:
anesthesia
sevoflurane
hypoxia
protein kinase mRNA
anti-apoptotic mRNA
transcriptional downregulation
Online Access:https://www.mdpi.com/2673-4087/6/1/9
Tags: Add Tag
No Tags, Be the first to tag this record!

Internet

https://www.mdpi.com/2673-4087/6/1/9

Similar Items