On the identification of differentially-active transcription factors from ATAC-seq data.

ATAC-seq has emerged as a rich epigenome profiling technique, and is commonly used to identify Transcription Factors (TFs) underlying given phenomena. A number of methods can be used to identify differentially-active TFs through the accessibility of their DNA-binding motif, however little is known o...

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Bibliographic Details
Main Authors: Felix Ezequiel Gerbaldo, Emanuel Sonder, Vincent Fischer, Selina Frei, Jiayi Wang, Katharina Gapp, Mark D Robinson, Pierre-Luc Germain
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2024-10-01
Series:PLoS Computational Biology
Online Access:https://doi.org/10.1371/journal.pcbi.1011971
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