Ex vivo-model design and evaluation of the sensitivity of blast cells to chemotherapy as a way to personalize the treatment of acute myeloid leukemia

Ex vivo-model design and evaluation of the sensitivity of blast cells to chemotherapy as a way to personalize the treatment of acute myeloid leukemia

Despite continuous attempts to improve therapy, the outcomes of acute myeloid leukemia remain almost unchanged over last decades. Drugs made with a more complete understanding of the biology of acute myeloid leukemia do not equal the hopes for better prognosis. The best results are achieved only wit...

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Bibliographic Details
Main Authors: A. S. Polyakov, Ya. A. Noskov, Yu. V. Nikitin, V. V. Tyrenko, S. N. Kolubaeva, A. N. Bogdanov, V. N. Semelev, O. R. Petrova, S. V. Bondarchuk, D. K. Zhogolev, A. D. Zolotarev, A. V. Kovalev, Yu. E. Puchkova
Format: Article
Language:Russian
Published: ABV-press 2019-07-01
Series:Онкогематология
Subjects:
acute myeloid leukemia
secondary acute myeloid leukemia
ex vivo model
drug sensitivity testing
genotoxicity
micronucleus test
fluorescence activated cell sorting
individualization of drug therapy
Online Access:https://oncohematology.abvpress.ru/ongm/article/view/349
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https://oncohematology.abvpress.ru/ongm/article/view/349

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