Design of Fe<sub>7</sub>S<sub>8</sub>@Lip Composite for the pH-Selective and Magnetically Targeted Programmed Release of H<sub>2</sub>S

The significance of hydrogen sulfide (H<sub>2</sub>S) release in vivo is multifaceted. It functions as a crucial gaseous signaling molecule with extensive physiological and pathological impacts within organisms. To create novel H<sub>2</sub>S-releasing materials, we synthesiz...

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Bibliographic Details
Main Authors: Shenghua Wang, Hanlin Wei, Jialian Li, Ning Liu, Zhiming Deng, Junqing Huang
Format: Article
Language:English
Published: MDPI AG 2025-03-01
Series:Magnetochemistry
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Online Access:https://www.mdpi.com/2312-7481/11/3/22
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Summary:The significance of hydrogen sulfide (H<sub>2</sub>S) release in vivo is multifaceted. It functions as a crucial gaseous signaling molecule with extensive physiological and pathological impacts within organisms. To create novel H<sub>2</sub>S-releasing materials, we synthesized Fe<sub>7</sub>S<sub>8</sub>@Lip, a slow-release gas nanocomposite, which exhibits stable and sustained H<sub>2</sub>S-release properties. Our gas releaser possesses selective H<sub>2</sub>S-release capabilities, and, notably, it can achieve effective H<sub>2</sub>S release under magnetic force with the assistance of a magnetic field. In conclusion, our findings indicate that Fe<sub>7</sub>S<sub>8</sub>@Lip can serve as an H<sub>2</sub>S slow-release nanocomposite, offering a potentially innovative approach for programmed H<sub>2</sub>S release in vivo.
ISSN:2312-7481