Peste des petits ruminants virus virulence is associated with an early inflammatory profile in the tonsils and cell cycle arrest in lymphoid tissue

Peste des petits ruminants virus virulence is associated with an early inflammatory profile in the tonsils and cell cycle arrest in lymphoid tissue

ABSTRACT Using a systems immunology approach, this study comprehensively explored the immunopathogenesis of peste des petits ruminants (PPR) focussing on strain-dependent differences in virulence. Saanen goats were infected either with the highly virulent (Morocco 2008 [MA08]) or the low-virulent (I...

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Bibliographic Details
Main Authors: Roger-Junior Eloiflin, Llorenç Grau-Roma, Vincent Lasserre, Sylvie Python, Stephanie Talker, Philippe Totte, Obdulio García- Nicolás, Artur Summerfield, Arnaud Bataille
Format: Article
Language:English
Published: American Society for Microbiology 2025-04-01
Series:Microbiology Spectrum
Subjects:
peste des petits ruminants
virulence
immunopathogenesis
goat
morbillivirus
Online Access:https://journals.asm.org/doi/10.1128/spectrum.03124-24
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https://journals.asm.org/doi/10.1128/spectrum.03124-24

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