Mycobacterium tuberculosis protein MoxR1 enhances virulence by inhibiting host cell death pathways and disrupting cellular bioenergetics

Mycobacterium tuberculosis protein MoxR1 enhances virulence by inhibiting host cell death pathways and disrupting cellular bioenergetics

Mycobacterium tuberculosis (M. tb) utilizes the multifunctionality of its protein factors to deceive the host. The unabated global incidence and prevalence of tuberculosis (TB) and the emergence of multidrug-resistant strains warrant the discovery of novel drug targets that can be exploited to manag...

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Bibliographic Details
Main Authors: Neha Quadir, Mohd. Shariq, Javaid Ahmad Sheikh, Jasdeep Singh, Neha Sharma, Seyed Ehtesham Hasnain, Nasreen Zafar Ehtesham
Format: Article
Language:English
Published: Taylor & Francis Group 2023-12-01
Series:Virulence
Subjects:
AAA+ family protein
chaperone
MAPK signalling
NFKB
proinflammatory cytokines
survival signalling
Online Access:https://www.tandfonline.com/doi/10.1080/21505594.2023.2180230
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https://www.tandfonline.com/doi/10.1080/21505594.2023.2180230

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