IN VITRO ASSESSMENT OF LONG-TERM EFFECTS OF CYTOTOXIC DRUGS ON MALE REPRODUCTIVE FUNCTION

IN VITRO ASSESSMENT OF LONG-TERM EFFECTS OF CYTOTOXIC DRUGS ON MALE REPRODUCTIVE FUNCTION

The purpose of the study was a comparative assessment of long-term toxic effects of cytotoxic drugs (anthracycline antibiotics, topoisomerase activity inhibitors, platinum and taxane complex compounds) on male reproductive function. Material and methods. 2.5-month-old male Wistar rats were used in t...

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Bibliographic Details
Main Authors: T. G. Borovskaya, V. E. Goldberg, M. E. Poluektova, Yu. A. Shchemerovа, A. V. Vychuzhanina, V. A. Grigoreva, O. V. Kollantay, S. I. Kamalova
Format: Article
Language:Russian
Published: Russian Academy of Sciences, Tomsk National Research Medical Center 2020-03-01
Series:Сибирский онкологический журнал
Subjects:
cytotoxic drugs
reproductive system status
long-term toxic effects
rats
Online Access:https://www.siboncoj.ru/jour/article/view/1323
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https://www.siboncoj.ru/jour/article/view/1323

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