ATP-release pannexin channels are gated by lysophospholipids

ATP-release pannexin channels are gated by lysophospholipids

In addition to its role as cellular energy currency, adenosine triphosphate (ATP) serves as an extracellular messenger that mediates diverse cell-to-cell communication. Compelling evidence supports that ATP is released from cells through pannexins, a family of membrane proteins that form heptameric...

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Bibliographic Details
Main Authors: Erik Henze, Russell N Burkhardt, Bennett William Fox, Tyler J Schwertfeger, Eric Gelsleichter, Kevin Michalski, Lydia Kramer, Margret Lenfest, Jordyn M Boesch, Hening Lin, Frank C Schroeder, Toshimitsu Kawate
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2025-05-01
Series:eLife
Subjects:
large pore channel
untargeted metabolomics
secretomics
inflammasome
lipid signaling
Online Access:https://elifesciences.org/articles/107067
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https://elifesciences.org/articles/107067

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