The role of GATA4 in mesenchymal stem cell senescence: A new frontier in regenerative medicine

The role of GATA4 in mesenchymal stem cell senescence: A new frontier in regenerative medicine

The Mesenchymal Stem Cell (MSC) is a multipotent progenitor cell with known differentiation potential towards various cell lineage, making it an appealing candidate for regenerative medicine. One major contributing factor to age-related MSC dysfunction is cellular senescence, which is the hallmark o...

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Bibliographic Details
Main Authors: M. Arockia Babu, Renuka Jyothi S, Irwanjot Kaur, Sachin Kumar, Naveen Sharma, M. Ravi Kumar, Pranchal Rajput, Haider Ali, Gaurav Gupta, Vetriselvan Subramaniyan, Ling Shing Wong, Vinoth Kumarasamy
Format: Article
Language:English
Published: Elsevier 2025-03-01
Series:Regenerative Therapy
Subjects:
GATA4
Mesenchymal stem cells
Stem cell aging
Cellular senescence
Transcription factors
Oxidative stress
Online Access:http://www.sciencedirect.com/science/article/pii/S2352320424002098
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