Exploring the ER channel protein Sec61: recent advances in pathophysiological significance and novel pharmacological inhibitors
The Sec61 complex, which is located on the membrane of the mammalian endoplasmic reticulum (ER), serves as a pivotal component of protein transport channels. It plays a central role in the transport of nascent peptides and precursor peptides to the ER. This process includes the directed movement of...
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| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Frontiers Media S.A.
2025-06-01
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| Series: | Frontiers in Pharmacology |
| Subjects: | |
| Online Access: | https://www.frontiersin.org/articles/10.3389/fphar.2025.1580086/full |
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