Metastatic Small Cell Carcinoma of the Urinary Bladder That Recurred in the Vagina 6 Years after Radical Cystectomy: A Case Report
Small cell carcinoma (SCC) of the urinary bladder is highly aggressive and portends a poor outcome. Herein, we report a patient with recurrent SCC of the urinary bladder who experienced an unusually long-term disease-free duration after radical cystectomy. The patient was a 60-year-old woman who had...
Saved in:
| Main Authors: | , , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Wiley
2018-01-01
|
| Series: | Case Reports in Urology |
| Online Access: | http://dx.doi.org/10.1155/2018/3069294 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| _version_ | 1832549621700755456 |
|---|---|
| author | Makoto Isono Keiichi Ito Shinsuke Hamada Masahiro Takahashi Hidenori Sasa Hideyuki Shimazaki Tomohiko Asano |
| author_facet | Makoto Isono Keiichi Ito Shinsuke Hamada Masahiro Takahashi Hidenori Sasa Hideyuki Shimazaki Tomohiko Asano |
| author_sort | Makoto Isono |
| collection | DOAJ |
| description | Small cell carcinoma (SCC) of the urinary bladder is highly aggressive and portends a poor outcome. Herein, we report a patient with recurrent SCC of the urinary bladder who experienced an unusually long-term disease-free duration after radical cystectomy. The patient was a 60-year-old woman who had undergone transurethral resection followed by radical cystectomy for muscle-invasive bladder cancer (high-grade urothelial carcinoma with adenocarcinomatous differentiation) 6 years prior; the surgical specimen had a negative surgical margin. She was referred to our hospital because of continuous bleeding from her vagina. Magnetic resonance imaging showed a mass located at the anterior wall of her residual vagina, a biopsy of which confirmed a pathological diagnosis of adenocarcinoma. The vaginal tumor and a section of the sigmoid colon were resected en bloc and were pathologically diagnosed as adenocarcinoma and SCC. We reevaluated the initial transurethral resection specimen and found SCC with foci of adenocarcinoma concomitant with high-grade urothelial carcinoma. Local recurrence and metastasis at the pelvic bone occurred 4 months later; although radiation therapy was performed, she died of the progressive disease. |
| format | Article |
| id | doaj-art-e8673867e2b64499a326fedd21fce33f |
| institution | Kabale University |
| issn | 2090-696X 2090-6978 |
| language | English |
| publishDate | 2018-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Case Reports in Urology |
| spelling | doaj-art-e8673867e2b64499a326fedd21fce33f2025-02-03T06:10:59ZengWileyCase Reports in Urology2090-696X2090-69782018-01-01201810.1155/2018/30692943069294Metastatic Small Cell Carcinoma of the Urinary Bladder That Recurred in the Vagina 6 Years after Radical Cystectomy: A Case ReportMakoto Isono0Keiichi Ito1Shinsuke Hamada2Masahiro Takahashi3Hidenori Sasa4Hideyuki Shimazaki5Tomohiko Asano6Department of Urology, National Defense Medical College, 3-2 Namiki, Tokorozawa, Saitama 359-8513, JapanDepartment of Urology, National Defense Medical College, 3-2 Namiki, Tokorozawa, Saitama 359-8513, JapanDepartment of Urology, National Defense Medical College, 3-2 Namiki, Tokorozawa, Saitama 359-8513, JapanDepartment of Urology, National Defense Medical College, 3-2 Namiki, Tokorozawa, Saitama 359-8513, JapanDepartment of Obstetrics and Gynecology, National Defense Medical College, 3-2 Namiki, Tokorozawa, Saitama 359-8513, JapanDepartment of Laboratory Medicine, National Defense Medical College, 3-2 Namiki, Tokorozawa, Saitama 359-8513, JapanDepartment of Urology, National Defense Medical College, 3-2 Namiki, Tokorozawa, Saitama 359-8513, JapanSmall cell carcinoma (SCC) of the urinary bladder is highly aggressive and portends a poor outcome. Herein, we report a patient with recurrent SCC of the urinary bladder who experienced an unusually long-term disease-free duration after radical cystectomy. The patient was a 60-year-old woman who had undergone transurethral resection followed by radical cystectomy for muscle-invasive bladder cancer (high-grade urothelial carcinoma with adenocarcinomatous differentiation) 6 years prior; the surgical specimen had a negative surgical margin. She was referred to our hospital because of continuous bleeding from her vagina. Magnetic resonance imaging showed a mass located at the anterior wall of her residual vagina, a biopsy of which confirmed a pathological diagnosis of adenocarcinoma. The vaginal tumor and a section of the sigmoid colon were resected en bloc and were pathologically diagnosed as adenocarcinoma and SCC. We reevaluated the initial transurethral resection specimen and found SCC with foci of adenocarcinoma concomitant with high-grade urothelial carcinoma. Local recurrence and metastasis at the pelvic bone occurred 4 months later; although radiation therapy was performed, she died of the progressive disease.http://dx.doi.org/10.1155/2018/3069294 |
| spellingShingle | Makoto Isono Keiichi Ito Shinsuke Hamada Masahiro Takahashi Hidenori Sasa Hideyuki Shimazaki Tomohiko Asano Metastatic Small Cell Carcinoma of the Urinary Bladder That Recurred in the Vagina 6 Years after Radical Cystectomy: A Case Report Case Reports in Urology |
| title | Metastatic Small Cell Carcinoma of the Urinary Bladder That Recurred in the Vagina 6 Years after Radical Cystectomy: A Case Report |
| title_full | Metastatic Small Cell Carcinoma of the Urinary Bladder That Recurred in the Vagina 6 Years after Radical Cystectomy: A Case Report |
| title_fullStr | Metastatic Small Cell Carcinoma of the Urinary Bladder That Recurred in the Vagina 6 Years after Radical Cystectomy: A Case Report |
| title_full_unstemmed | Metastatic Small Cell Carcinoma of the Urinary Bladder That Recurred in the Vagina 6 Years after Radical Cystectomy: A Case Report |
| title_short | Metastatic Small Cell Carcinoma of the Urinary Bladder That Recurred in the Vagina 6 Years after Radical Cystectomy: A Case Report |
| title_sort | metastatic small cell carcinoma of the urinary bladder that recurred in the vagina 6 years after radical cystectomy a case report |
| url | http://dx.doi.org/10.1155/2018/3069294 |
| work_keys_str_mv | AT makotoisono metastaticsmallcellcarcinomaoftheurinarybladderthatrecurredinthevagina6yearsafterradicalcystectomyacasereport AT keiichiito metastaticsmallcellcarcinomaoftheurinarybladderthatrecurredinthevagina6yearsafterradicalcystectomyacasereport AT shinsukehamada metastaticsmallcellcarcinomaoftheurinarybladderthatrecurredinthevagina6yearsafterradicalcystectomyacasereport AT masahirotakahashi metastaticsmallcellcarcinomaoftheurinarybladderthatrecurredinthevagina6yearsafterradicalcystectomyacasereport AT hidenorisasa metastaticsmallcellcarcinomaoftheurinarybladderthatrecurredinthevagina6yearsafterradicalcystectomyacasereport AT hideyukishimazaki metastaticsmallcellcarcinomaoftheurinarybladderthatrecurredinthevagina6yearsafterradicalcystectomyacasereport AT tomohikoasano metastaticsmallcellcarcinomaoftheurinarybladderthatrecurredinthevagina6yearsafterradicalcystectomyacasereport |