Nanomechanical Characterization of Canine Femur Bone for Strain Rate Sensitivity in the Quasistatic Range under Dry versus Wet Conditions
As a strain rate-dependent material, bone has a different mechanical response to various loads. Our aim was to evaluate the effect of water and different loading/unloading rates on the nanomechanical properties of canine femur cortical bone. Six cross-sections were cut from the diaphysis of six dog...
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| Format: | Article |
| Language: | English |
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Wiley
2012-01-01
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| Series: | International Journal of Biomaterials |
| Online Access: | http://dx.doi.org/10.1155/2012/415230 |
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| author | Kun-Lin Lee Marta Baldassarri Nikhil Gupta Dinesh Pinisetty Malvin N. Janal Nick Tovar Paulo G. Coelho |
| author_facet | Kun-Lin Lee Marta Baldassarri Nikhil Gupta Dinesh Pinisetty Malvin N. Janal Nick Tovar Paulo G. Coelho |
| author_sort | Kun-Lin Lee |
| collection | DOAJ |
| description | As a strain rate-dependent material, bone has a different mechanical response to various loads. Our aim was to evaluate the effect of water and different loading/unloading rates on the nanomechanical properties of canine femur cortical bone. Six cross-sections were cut from the diaphysis of six dog femurs and were nanoindented in their cortical area. Both dry and wet conditions were taken into account for three quasistatic trapezoid profiles with a maximum force of 2000 μN (holding time = 30 s) at loading/unloading rates of 10, 100, and 1000 μN/s, respectively. For each specimen, 254±9 (mean ± SD) indentations were performed under different loading conditions. Significant differences were found for the elastic modulus and hardness between wet and dry conditions (P<0.001). No influence of the loading/unloading rates was observed between groups except for the elastic modulus measured at 1000 μN/s rate under dry conditions (P<0.001) and for the hardness measured at a rate of 10 μN/s under wet conditions (P<0.001). Therefore, for a quasistatic test with peak load of 2000 μN held for 30 s, it is recommended to nanoindent under wet conditions at a loading/unloading rate of 100–1000 μN/s, so the reduced creep effect allows for a more accurate computation of mechanical properties. |
| format | Article |
| id | doaj-art-e82013e7d0cd494693fdffa9f1f3cb5a |
| institution | Kabale University |
| issn | 1687-8787 1687-8795 |
| language | English |
| publishDate | 2012-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | International Journal of Biomaterials |
| spelling | doaj-art-e82013e7d0cd494693fdffa9f1f3cb5a2025-02-03T01:32:02ZengWileyInternational Journal of Biomaterials1687-87871687-87952012-01-01201210.1155/2012/415230415230Nanomechanical Characterization of Canine Femur Bone for Strain Rate Sensitivity in the Quasistatic Range under Dry versus Wet ConditionsKun-Lin Lee0Marta Baldassarri1Nikhil Gupta2Dinesh Pinisetty3Malvin N. Janal4Nick Tovar5Paulo G. Coelho6Composite Materials and Mechanics Laboratory, Mechanical and Aerospace Engineering Department, Polytechnic Institute of New York University, Brooklyn, NY 11201, USADepartment of Biomaterials and Biomimetics, College of Dentistry, New York University, 345 24th Street 813a, New York, NY 10010, USAComposite Materials and Mechanics Laboratory, Mechanical and Aerospace Engineering Department, Polytechnic Institute of New York University, Brooklyn, NY 11201, USAComposite Materials and Mechanics Laboratory, Mechanical and Aerospace Engineering Department, Polytechnic Institute of New York University, Brooklyn, NY 11201, USADepartment of Epidemiology, New York University, NY 10010, USADepartment of Biomaterials and Biomimetics, College of Dentistry, New York University, 345 24th Street 813a, New York, NY 10010, USADepartment of Biomaterials and Biomimetics, College of Dentistry, New York University, 345 24th Street 813a, New York, NY 10010, USAAs a strain rate-dependent material, bone has a different mechanical response to various loads. Our aim was to evaluate the effect of water and different loading/unloading rates on the nanomechanical properties of canine femur cortical bone. Six cross-sections were cut from the diaphysis of six dog femurs and were nanoindented in their cortical area. Both dry and wet conditions were taken into account for three quasistatic trapezoid profiles with a maximum force of 2000 μN (holding time = 30 s) at loading/unloading rates of 10, 100, and 1000 μN/s, respectively. For each specimen, 254±9 (mean ± SD) indentations were performed under different loading conditions. Significant differences were found for the elastic modulus and hardness between wet and dry conditions (P<0.001). No influence of the loading/unloading rates was observed between groups except for the elastic modulus measured at 1000 μN/s rate under dry conditions (P<0.001) and for the hardness measured at a rate of 10 μN/s under wet conditions (P<0.001). Therefore, for a quasistatic test with peak load of 2000 μN held for 30 s, it is recommended to nanoindent under wet conditions at a loading/unloading rate of 100–1000 μN/s, so the reduced creep effect allows for a more accurate computation of mechanical properties.http://dx.doi.org/10.1155/2012/415230 |
| spellingShingle | Kun-Lin Lee Marta Baldassarri Nikhil Gupta Dinesh Pinisetty Malvin N. Janal Nick Tovar Paulo G. Coelho Nanomechanical Characterization of Canine Femur Bone for Strain Rate Sensitivity in the Quasistatic Range under Dry versus Wet Conditions International Journal of Biomaterials |
| title | Nanomechanical Characterization of Canine Femur Bone for Strain Rate Sensitivity in the Quasistatic Range under Dry versus Wet Conditions |
| title_full | Nanomechanical Characterization of Canine Femur Bone for Strain Rate Sensitivity in the Quasistatic Range under Dry versus Wet Conditions |
| title_fullStr | Nanomechanical Characterization of Canine Femur Bone for Strain Rate Sensitivity in the Quasistatic Range under Dry versus Wet Conditions |
| title_full_unstemmed | Nanomechanical Characterization of Canine Femur Bone for Strain Rate Sensitivity in the Quasistatic Range under Dry versus Wet Conditions |
| title_short | Nanomechanical Characterization of Canine Femur Bone for Strain Rate Sensitivity in the Quasistatic Range under Dry versus Wet Conditions |
| title_sort | nanomechanical characterization of canine femur bone for strain rate sensitivity in the quasistatic range under dry versus wet conditions |
| url | http://dx.doi.org/10.1155/2012/415230 |
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