The effect of immune selection on the structure of the meningococcal opa protein repertoire.

The opa genes of the Gram negative bacterium Neisseria meningitidis encode Opacity-associated outer membrane proteins whose role is to promote adhesion to the human host tissue during colonisation and invasion. Each meningococcus contains 3-4 opa loci, each of which may be occupied by one of a large...

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Bibliographic Details
Main Authors: Martin J Callaghan, Caroline O Buckee, Keith A Jolley, Paula Kriz, Martin C J Maiden, Sunetra Gupta
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2008-03-01
Series:PLoS Pathogens
Online Access:https://journals.plos.org/plospathogens/article/file?id=10.1371/journal.ppat.1000020&type=printable
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