Development of broad‐spectrum human monoclonal antibodies for rabies post‐exposure prophylaxis

Development of broad‐spectrum human monoclonal antibodies for rabies post‐exposure prophylaxis

Abstract Currently available rabies post‐exposure prophylaxis (PEP) for use in humans includes equine or human rabies immunoglobulins (RIG). The replacement of RIG with an equally or more potent and safer product is strongly encouraged due to the high costs and limited availability of existing RIG....

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Main Authors: Paola De Benedictis, Andrea Minola, Elena Rota Nodari, Roberta Aiello, Barbara Zecchin, Angela Salomoni, Mathilde Foglierini, Gloria Agatic, Fabrizia Vanzetta, Rachel Lavenir, Anthony Lepelletier, Emma Bentley, Robin Weiss, Giovanni Cattoli, Ilaria Capua, Federica Sallusto, Edward Wright, Antonio Lanzavecchia, Hervé Bourhy, Davide Corti
Format: Article
Language:English
Published: Springer Nature 2016-03-01
Series:EMBO Molecular Medicine
Subjects:
human monoclonal antibody
lyssaviruses
post‐exposure prophylaxis
rabies
Online Access:https://doi.org/10.15252/emmm.201505986
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https://doi.org/10.15252/emmm.201505986

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