Oleic acid restores the impaired antitumor immunity of γδ-T cells induced by palmitic acid

Oleic acid restores the impaired antitumor immunity of γδ-T cells induced by palmitic acid

Abstract Dietary fatty acids (FAs) are associated with the therapeutic intervention under various health conditions. Human γδ-T cells are indispensable for immunosurveillance toward malignant cells. However, their impact on γδ-T cell metabolism and function remains poorly unexplored. Here, we applie...

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Main Authors: Yanmei Zhang, Zheng Xiang, Yan Xu, Lo Sha Cheung, Xiwei Wang, Manni Wang, Howard Ho Wai Wong, Zhenyao Zhu, Wenyue Zhang, Yifan Gao, Xianze Luo, Yin Celeste Cheuk, Yixin Zhou, Xianfeng Zha, Yashi Chen, Man Li, Feifei Luo, Yiwei Chu, Yu-Lung Lau, Yinping Liu, Wenwei Tu
Format: Article
Language:English
Published: Nature Publishing Group 2025-07-01
Series:Signal Transduction and Targeted Therapy
Online Access:https://doi.org/10.1038/s41392-025-02295-8
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