Genetic Variations of Gene Associated with Adverse Drug Reactions to Valproic Acid in Korean Epileptic Patients

Genetic Variations of Gene Associated with Adverse Drug Reactions to Valproic Acid in Korean Epileptic Patients

The multidrug resistance protein 2 (MRP2, ABCC2) gene may determine individual susceptibility to adverse drug reactions (ADRs) in the central nervous system (CNS) by limiting brain access of antiepileptic drugs, especially valproic acid (VPA). Our objective was to investigate the effect of ABCC2 pol...

Full description

Saved in:
Bibliographic Details
Main Authors: Ji Hyun Yi, Yang-Je Cho, Won-Joo Kim, Min Goo Lee, Ji Hyun Lee
Format: Article
Language:English
Published: BioMed Central 2013-12-01
Series:Genomics & Informatics
Subjects:
drug toxicity
epilepsy
genetic polymorphism
MRP2
valproic acid
Online Access:http://genominfo.org/upload/pdf/gni-11-254.pdf
Tags: Add Tag
No Tags, Be the first to tag this record!

Internet

http://genominfo.org/upload/pdf/gni-11-254.pdf

Similar Items