Possibilities of Predicting Methotrexate-associated Toxicity in Oncohematology Based on Molecular Genetic Testing Methods

The development of highly effective protocols for the treatment of acute lymphoblastic leukemia (ALL) and non-Hodgkin lymphomas (NHL) followed the path of escalation of doses of cytostatic agents and improvement of supportive care. Methotrexate (MTX), used in high doses (1000–5000 mg/m2), radically...

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Bibliographic Details
Main Authors: Zarui K. Simavonyan, Timur T. Valiev, Marina I. Savelyeva, Sherzod P. Abdullaev, Svetlana R. Varfolomeeva
Format: Article
Language:Russian
Published: Union of pediatricians of Russia 2024-11-01
Series:Педиатрическая фармакология
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Online Access:https://www.pedpharma.ru/jour/article/view/2528
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