Sleep drive is coupled to tissue damage via shedding of Caenorhabditis elegans EGFR ligand SISS-1

Abstract The benefits of sleep extend beyond the nervous system. Peripheral tissues impact sleep regulation, and increased sleep is observed in response to damaging conditions, even those that selectively affect non-neuronal cells. However, the ‘sleep need’ signal released by stressed tissues is not...

Full description

Saved in:
Bibliographic Details
Main Authors: Andrew J. Hill, Bryan Robinson, Jesse G. Jones, Paul W. Sternberg, Cheryl Van Buskirk
Format: Article
Language:English
Published: Nature Portfolio 2024-12-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-024-55252-4
Tags: Add Tag
No Tags, Be the first to tag this record!