Impaired cardiac pumping function and increased afterload as determinants of early hemodynamic alterations in Cushing disease

Impaired cardiac pumping function and increased afterload as determinants of early hemodynamic alterations in Cushing disease

Abstract The long-term hypercortisolemia of Cushing disease (CD) may lead to hemodynamic disorders by increasing subclinical cardiac and vascular dysfunction. The purpose of this observational cohort study was to assess the relationship between hemodynamic parameters evaluated via impedance cardiogr...

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Main Authors: Agnieszka Włochacz, Paweł Krzesiński, Beata Uziębło-Życzkowska, Przemysław Witek, Grzegorz Zieliński, Anna Kazimierczak, Robert Wierzbowski, Małgorzata Banak, Grzegorz Gielerak
Format: Article
Language:English
Published: Nature Portfolio 2025-01-01
Series:Scientific Reports
Subjects:
Cushing disease
Echocardiography
Global longitudinal strain
Hemodynamic disorders
Impedance cardiography
Pituitary neuroendocrine tumor
Online Access:https://doi.org/10.1038/s41598-024-84888-x
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https://doi.org/10.1038/s41598-024-84888-x

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