Loading diltiazem onto surface-modified nanostructured lipid carriers to evaluate its apoptotic, cytotoxic, and inflammatory effects on human breast cancer cells

Loading diltiazem onto surface-modified nanostructured lipid carriers to evaluate its apoptotic, cytotoxic, and inflammatory effects on human breast cancer cells

The main goal of cancer treatment is to ensure that the drug reaches the tumor tissue and to reduce the side effects of the drug. This study was conducted to synthesize a novel nanostructured lipid carrier modified with chitosan-folate to deliver diltiazem to cancer cell lines and to evaluate its an...

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Bibliographic Details
Main Authors: Vahid Pouresmaeil, Marwa Mawlood Salman Al-zand, Aida Pouresmaeil, Seyedeh Samira Saghravanian, Masoud Homayouni Tabrizi
Format: Article
Language:English
Published: AIMS Press 2024-07-01
Series:AIMS Molecular Science
Subjects:
diltiazem
nanostructured lipid carriers
anti-inflammatory effect
apoptosis
breast cancer cells
Online Access:https://www.aimspress.com/article/doi/10.3934/molsci.2024014?viewType=HTML
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