Chinese herbal formula Huayu-Qiangshen-Tongbi decoction ameliorates rheumatoid arthritis through enhancing the release of exosomal miR-125b-5p derived from adipose-derived stem cells by CD63

Chinese herbal formula Huayu-Qiangshen-Tongbi decoction ameliorates rheumatoid arthritis through enhancing the release of exosomal miR-125b-5p derived from adipose-derived stem cells by CD63

Abstract Background Rheumatoid arthritis (RA) is a chronic and multifactorial inflammatory disease inducing damages in joints and extra-articular organs. Our previous study has revealed that Huayu-Qiangshen-Tongbi decoction (HQT) ameliorates RA through upregulating microRNA (miRNA) miR-125b-5p to su...

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Bibliographic Details
Main Authors: Wu Xiao-dong, Liang You-bang, Niu Yun-bao, Yang Yi-hong, Huang Wen-zhi, Wang Mao-jie, Mei Li-yan, Gao Kai-xin, Huang Run-yue, Chen Xiu-min
Format: Article
Language:English
Published: BMC 2025-07-01
Series:Biological Research
Subjects:
Arthritis
Rheumatoid
Huayu-Qiangshen-Tongbi decoction
Exosomal miR-125b-5p
Adipose-derived stem cells
CD63 protein
Online Access:https://doi.org/10.1186/s40659-025-00628-z
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https://doi.org/10.1186/s40659-025-00628-z

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