Miliary Tuberculosis Induced Acute Liver Failure
Hepatobiliary tuberculosis is uncommon even in endemic countries. It is associated with a high mortality and is even diagnosed early in the disease course. Acute liver failure (ALF) caused by tuberculosis bacilli has been reported in only a few reports. All previous cases have been diagnosed by post...
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| Main Authors: | , , , , , , , , |
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| Format: | Article |
| Language: | English |
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Wiley
2015-01-01
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| Series: | Case Reports in Infectious Diseases |
| Online Access: | http://dx.doi.org/10.1155/2015/759341 |
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| _version_ | 1832549827852894208 |
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| author | Tayfur Toptas Birkan Ilhan Huseyin Bilgin Elif Dincses Osman Ozdogan Isik Kaygusuz-Atagunduz Zekaver Odabasi Volkan Korten Tulin Firatli-Tuglular |
| author_facet | Tayfur Toptas Birkan Ilhan Huseyin Bilgin Elif Dincses Osman Ozdogan Isik Kaygusuz-Atagunduz Zekaver Odabasi Volkan Korten Tulin Firatli-Tuglular |
| author_sort | Tayfur Toptas |
| collection | DOAJ |
| description | Hepatobiliary tuberculosis is uncommon even in endemic countries. It is associated with a high mortality and is even diagnosed early in the disease course. Acute liver failure (ALF) caused by tuberculosis bacilli has been reported in only a few reports. All previous cases have been diagnosed by postmortem examination. Time to antituberculosis treatment is very critical. In case of suggestive findings on clinical and radiologic examination, antituberculosis treatment should be initiated immediately. Drug use can be a challenge in patients with ALF. However, as long as the other possible causes of ALF can be excluded and hepatotoxic drugs were avoided during the early course of treatment, such a highly fatal presentation of tuberculosis can be treated safely. Here, we report a case of acute liver failure as a presentation of miliary tuberculosis. He was treated successfully with antituberculosis treatment. |
| format | Article |
| id | doaj-art-e72ec51bcdab4e7f94c704004ed335af |
| institution | Kabale University |
| issn | 2090-6625 2090-6633 |
| language | English |
| publishDate | 2015-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Case Reports in Infectious Diseases |
| spelling | doaj-art-e72ec51bcdab4e7f94c704004ed335af2025-02-03T06:08:36ZengWileyCase Reports in Infectious Diseases2090-66252090-66332015-01-01201510.1155/2015/759341759341Miliary Tuberculosis Induced Acute Liver FailureTayfur Toptas0Birkan Ilhan1Huseyin Bilgin2Elif Dincses3Osman Ozdogan4Isik Kaygusuz-Atagunduz5Zekaver Odabasi6Volkan Korten7Tulin Firatli-Tuglular8Department of Hematology, Van Training and Research Hospital, 65300 Van, TurkeyDepartment of Internal Medicine, Marmara University Hospital, Istanbul, TurkeyDepartment of Infectious Diseases, Marmara University Hospital, Istanbul, TurkeyDepartment of Internal Medicine, Marmara University Hospital, Istanbul, TurkeyDepartment of Gastroenterology, Marmara University Hospital, Istanbul, TurkeyDepartment of Hematology, Marmara University Hospital, Istanbul, TurkeyDepartment of Infectious Diseases, Marmara University Hospital, Istanbul, TurkeyDepartment of Infectious Diseases, Marmara University Hospital, Istanbul, TurkeyDepartment of Hematology, Marmara University Hospital, Istanbul, TurkeyHepatobiliary tuberculosis is uncommon even in endemic countries. It is associated with a high mortality and is even diagnosed early in the disease course. Acute liver failure (ALF) caused by tuberculosis bacilli has been reported in only a few reports. All previous cases have been diagnosed by postmortem examination. Time to antituberculosis treatment is very critical. In case of suggestive findings on clinical and radiologic examination, antituberculosis treatment should be initiated immediately. Drug use can be a challenge in patients with ALF. However, as long as the other possible causes of ALF can be excluded and hepatotoxic drugs were avoided during the early course of treatment, such a highly fatal presentation of tuberculosis can be treated safely. Here, we report a case of acute liver failure as a presentation of miliary tuberculosis. He was treated successfully with antituberculosis treatment.http://dx.doi.org/10.1155/2015/759341 |
| spellingShingle | Tayfur Toptas Birkan Ilhan Huseyin Bilgin Elif Dincses Osman Ozdogan Isik Kaygusuz-Atagunduz Zekaver Odabasi Volkan Korten Tulin Firatli-Tuglular Miliary Tuberculosis Induced Acute Liver Failure Case Reports in Infectious Diseases |
| title | Miliary Tuberculosis Induced Acute Liver Failure |
| title_full | Miliary Tuberculosis Induced Acute Liver Failure |
| title_fullStr | Miliary Tuberculosis Induced Acute Liver Failure |
| title_full_unstemmed | Miliary Tuberculosis Induced Acute Liver Failure |
| title_short | Miliary Tuberculosis Induced Acute Liver Failure |
| title_sort | miliary tuberculosis induced acute liver failure |
| url | http://dx.doi.org/10.1155/2015/759341 |
| work_keys_str_mv | AT tayfurtoptas miliarytuberculosisinducedacuteliverfailure AT birkanilhan miliarytuberculosisinducedacuteliverfailure AT huseyinbilgin miliarytuberculosisinducedacuteliverfailure AT elifdincses miliarytuberculosisinducedacuteliverfailure AT osmanozdogan miliarytuberculosisinducedacuteliverfailure AT isikkaygusuzatagunduz miliarytuberculosisinducedacuteliverfailure AT zekaverodabasi miliarytuberculosisinducedacuteliverfailure AT volkankorten miliarytuberculosisinducedacuteliverfailure AT tulinfiratlituglular miliarytuberculosisinducedacuteliverfailure |