Organ-targeted biomarkers of sepsis: A systematic review reveals the value of inflammation and lipid metabolic dysregulation

Organ-targeted biomarkers of sepsis: A systematic review reveals the value of inflammation and lipid metabolic dysregulation

Sepsis, a life-threatening systemic inflammatory response to infection, progresses to multiorgan dysfunction involving the heart, lungs, kidneys, brain, and liver. Its heterogeneous pathogenesis involves intertwined pathways such as inflammationmetabolism imbalance, immune dysregulation, mitochondr...

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Bibliographic Details
Main Authors: Zhixin Xu, Jingdi Zhang, Zhan Li, Hongzheng Wu, Honglin Xu, Ye Guo, Yongzhe Li
Format: Article
Language:English
Published: Elsevier 2025-09-01
Series:Pharmacological Research
Subjects:
Sepsis
Inflammation–metabolism imbalance
Lipid metabolism
Multiomics
Online Access:http://www.sciencedirect.com/science/article/pii/S1043661825003421
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