β-glucan induced trained immunity enhances antibody levels in a vaccination model in mice.

Trained immunity improves disease resistance by strengthening our first line of defense, the innate immune system. Innate immune cells, predominantly macrophages, are epigenetically and metabolically rewired by β-glucan, a fungal cell wall component, to induce trained immunity. These trained macroph...

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Bibliographic Details
Main Authors: Jainu Ajit, Qing Chen, Trevor Ung, Matthew Rosenberger, Jeremiah Kim, Ani Solanki, Jingjing Shen, Aaron P Esser Kahn
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2025-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0323376
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