Exploitation of Unconventional CD8 T-Cell Responses Induced by Engineered Cytomegaloviruses for the Development of an HIV-1 Vaccine
After four decades of intensive research, traditional vaccination strategies for HIV-1 remain ineffective due to HIV-1′s extraordinary genetic diversity and complex immune evasion mechanisms. Cytomegaloviruses (CMV) have emerged as a novel type of vaccine vector with unique advantages due to CMV per...
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Main Authors: | Joseph Bruton, Tomáš Hanke |
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Format: | Article |
Language: | English |
Published: |
MDPI AG
2025-01-01
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Series: | Vaccines |
Subjects: | |
Online Access: | https://www.mdpi.com/2076-393X/13/1/72 |
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