Exploitation of Unconventional CD8 T-Cell Responses Induced by Engineered Cytomegaloviruses for the Development of an HIV-1 Vaccine

After four decades of intensive research, traditional vaccination strategies for HIV-1 remain ineffective due to HIV-1′s extraordinary genetic diversity and complex immune evasion mechanisms. Cytomegaloviruses (CMV) have emerged as a novel type of vaccine vector with unique advantages due to CMV per...

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Bibliographic Details
Main Authors: Joseph Bruton, Tomáš Hanke
Format: Article
Language:English
Published: MDPI AG 2025-01-01
Series:Vaccines
Subjects:
Online Access:https://www.mdpi.com/2076-393X/13/1/72
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