Choroid plexus organoids reveal mechanisms of Streptococcus suis translocation at the blood-cerebrospinal fluid barrier

Abstract Streptococcus suis is a globally emerging zoonotic pathogen that can cause invasive disease commonly associated with meningitis in pigs and humans. To cause meningitis, S. suis must invade the central nervous system (CNS) by crossing the neurovascular unit, also known as the blood-brain bar...

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Bibliographic Details
Main Authors: Tiantong Zhao, Laura Pellegrini, Bart van der Hee, Jos Boekhorst, Aline Fernandes, Sylvia Brugman, Peter van Baarlen, Jerry M. Wells
Format: Article
Language:English
Published: BMC 2025-02-01
Series:Fluids and Barriers of the CNS
Online Access:https://doi.org/10.1186/s12987-025-00627-y
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