An Overview of Live Attenuated Recombinant Pseudorabies Viruses for Use as Novel Vaccines

Pseudorabies virus (PRV) is a double-stranded, DNA-based swine virus with a genome approximating 150 kb in size. PRV has many nonessential genes which can be replaced with genes encoding heterologous antigens but without deleterious effects on virus propagation. Recombinant PRVs expressing both nati...

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Bibliographic Details
Main Authors: Bo Dong, Dante S. Zarlenga, Xiaofeng Ren
Format: Article
Language:English
Published: Wiley 2014-01-01
Series:Journal of Immunology Research
Online Access:http://dx.doi.org/10.1155/2014/824630
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