Tracking Stability Using Shewhart Charts to Elucidate Trending Patterns in Glyceryl Guaiacolate Assay: Paving the Way for Quality Improvement in Medicinal Chemical Industry

Shewhart charts are a crucial part of statistical process control, or SPC, which tracks and regulates the pharmaceutical compound’s inspection properties. It serves to shed light on the process’s present state and, if necessary, the future improvements that will be needed. The trending pattern for...

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Bibliographic Details
Main Author: Mostafa Essam Eissa
Format: Article
Language:English
Published: Prensip Publishing 2024-11-01
Series:Acta Natura et Scientia
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Online Access:https://prensipjournals.com/ojs/index.php/actanatsci/article/view/314
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Summary:Shewhart charts are a crucial part of statistical process control, or SPC, which tracks and regulates the pharmaceutical compound’s inspection properties. It serves to shed light on the process’s present state and, if necessary, the future improvements that will be needed. The trending pattern for the glyceryl guaiacolate assay is the main subject of this investigation. SPC software is used in this work. Following the selection of the most appropriate underlying distribution, Individual-Moving Range (I-MR) charts are used as a trending method for the data. Since some batches in the time series sequence show indications of out-of-control points, improvements are needed to enhance the quality of inspection attributes. Accordingly, capability analysis will not be relied on at this stage till the stabilization of the process. This study highlights the vital role of control charts in ensuring the quality of chemical materials. It contributes to building a robust industrial regulatory system by analyzing the quality of medicinal compounds from chemical manufacturers, especially in developing countries.
ISSN:2718-0638